IMSI – Advanced Sperm Selection for Better IVF Success
Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced technique used in In Vitro Fertilization (IVF) to select the best quality sperm for injection into the egg. Unlike traditional ICSI, IMSI uses a high-magnification microscope (over 6000x) to evaluate sperm in great detail, allowing embryologists to pick the most structurally normal sperm.
At Radha Hospital & Fertility Center, Dr. Aishwarya Yerram offers IMSI to couples who need the highest precision in sperm selection for improved fertilization and pregnancy outcomes.
What is IMSI?
IMSI (Intracytoplasmic Morphologically Selected Sperm Injection) is an advanced version of ICSI (Intracytoplasmic Sperm Injection).
In IMSI, sperm are examined under a very high-powered microscope (over 6000x magnification) to look for even the smallest structural defects. This helps embryologists select the healthiest and most normal sperm for injection into the egg, improving fertilization and embryo quality.
Who Needs IMSI?
IMSI is recommended for:
Couples with severe male infertility (very poor sperm morphology).
Repeated IVF or ICSI failures.
Unexplained infertility with poor embryo quality in previous cycles.
Men with high DNA fragmentation in sperm.
Couples with recurrent pregnancy loss.
How Does IMSI Work?
Ovarian Stimulation & Egg Retrieval – Similar to IVF/ICSI, eggs are collected from the female partner.
High-Magnification Sperm Screening – Sperm are examined under a microscope with over 6000x magnification, compared to the 400x used in conventional ICSI.
Selection of Best Sperm – Only the healthiest and most morphologically normal sperm are chosen.
Microinjection –A selected sperm is injected directly into the egg.
Embryo Development & Transfer – The resulting embryo is grown in the lab and transferred to the uterus.
Benefits of IMSI
Better Sperm Selection: Ensures only morphologically normal sperm are used.
Improved Fertilization: Increases the chances of healthy embryo formation.
Reduced Miscarriage Risk: Lower risk of chromosomal abnormalities and early pregnancy loss.
Higher Pregnancy Rates: Especially for couples with previous failed IVF or ICSI attempts
Pros & Cons Of IMSI
Pros of IMSI
Better sperm selection: Helps choose the healthiest sperm for fertilization.
Higher embryo quality: Increases the chances of developing healthy embryos.
Improved pregnancy rates: Especially in couples with previous IVF/ICSI failures.
Reduced risk of miscarriage: By selecting sperm with fewer abnormalities.
Helpful in severe male infertility: Works well when sperm quality is very poor.
Cons of IMSI
Higher cost: Slightly more expensive than conventional ICSI.
Longer procedure time: Takes more time for sperm selection under high magnification.
Limited availability: Requires advanced lab equipment and expertise
Why Choose Radha Hospital & Fertility Center for IMSI?
Expertise of Dr. Aishwarya Yerram in advanced reproductive techniques.
State-of-the-art embryology lab with high-resolution microscopes.
Personalized care for couples with complex infertility issues.
Book Your IMSI Consultation
If you’ve experienced failed IVF cycles or are dealing with severe male infertility, IMSI can greatly improve your chances of success.
Schedule a consultation with Dr. Aishwarya Yerram at Radha Hospital & Fertility Center to learn if IMSI is right for you.