Tacrolimus in Fertility
At Radha Hospital & Fertility Center, we offer advanced reproductive treatments to help couples overcome complex fertility challenges. One such therapy is Tacrolimus, an immune-modulating medicine that can improve implantation and pregnancy outcomes in women with immune-related fertility issues.
What is Tacrolimus?
Tacrolimus is a medication originally developed to prevent organ rejection in transplant patients by suppressing the immune system. In fertility care, it is used in carefully monitored doses to help women whose immune system is overactive and may attack embryos, preventing implantation or causing miscarriage.
Why is Tacrolimus Used in Fertility Treatments?
For some women, immune system imbalance is a hidden reason for infertility, repeated IVF failures, or recurrent miscarriages. Overactive immune cells (such as T-cells and NK cells) may attack the developing embryo, making it difficult to sustain a pregnancy.
Tacrolimus helps by:
Suppressing harmful immune responses against the embryo.
Supporting implantation during IVF or ICSI treatments.
Reducing the chances of recurrent pregnancy loss.
Improving the success rates in women with immune-related infertility.
When is Tacrolimus Recommended?
Your doctor may suggest Tacrolimus if you have:
Recurrent pregnancy loss (two or more miscarriages).
Repeated IVF/ICSI failures despite good-quality embryos.
Immune-related disorders such as autoimmune diseases (lupus, rheumatoid arthritis, thyroid autoimmunity).
High NK cell or T-cell activity detected in fertility immunology tests.
Unexplained infertility where other treatments have not worked.
How is Tacrolimus Given?
Tacrolimus is usually prescribed in low oral doses (capsules).
It is started before embryo transfer or early in pregnancy, depending on the case.
Treatment is closely monitored with regular blood tests to check drug levels, kidney function, and overall health.
Benefits of Tacrolimus in Fertility
Improves implantation rates in IVF/ICSI cycles.
Reduces the risk of immune-related miscarriages.
Balances the immune system without harming the baby.
Provides hope for women with unexplained infertility.
Safe when prescribed under specialist supervision.
Possible Side Effects of Tacrolimus
Like any medication, Tacrolimus may cause side effects, but at fertility doses, these are usually mild and manageable.
Common side effects:
Mild headache or dizziness
Nausea or stomach upset
Increased blood sugar levels
Tiredness
Rare but possible side effects:
High blood pressure
Kidney function changes
Increased risk of infections (due to lowered immunity)
At Radha Hospital, we ensure close monitoring to minimize risks and adjust treatment as needed.
Why Choose Radha Hospital & Fertility Center for Tacrolimus Therapy?
Expertise in Reproductive Immunology and Fertility Medicine
Personalized treatment plans for immune-related infertility
Advanced testing to detect hidden immune causes of infertility
Safe use of immune-modulating drugs with continuous monitoring
Compassionate care and full guidance at every stage of treatment
Our Commitment
At Radha Hospital & Fertility Center, we believe in offering the latest scientific advancements to help couples achieve parenthood. Tacrolimus therapy has given new hope to many couples struggling with unexplained infertility, repeated IVF failures, or recurrent miscarriages.
With our expertise, advanced monitoring, and personalized care, we aim to make your journey toward parenthood safe, supported, and successful.
Book an Appointment
At Radha Hospital & Fertility Center, we make it easy for you to connect with our specialists. Whether you need a consultation for women’s health, fertility treatments, or advanced care, our expert team is here to guide you.